Feifei Xiao,
Associate Professor
Department:
PHHP-COM BIOSTATISTICS
Business Phone:
(352) 294-5917
Business Email:
feifeixiao@ufl.edu
About Feifei Xiao
Dr. Feifei Xiao is an Associate Professor in the Department of Biostatistics with the Artificial Intelligence Initiative. Dr. Xiao’s research mainly focuses on the development and application of powerful and efficient statistical methods for high throughput genetics and genomics data, driven by the challenges arising from the modern biotechnologies such as next-generation sequencing and single cell sequencing. Dr. Xiao is interested in exploring the advantages of machine learning methods and approaches in public health related outcomes, especially in handling high throughput data. Dr. Xiao works on the next generation chromosomal copy number variation detection, integrative analysis of ‘omics’ data (such as SNP, methylation and expression data), and neuroimaging genetic data analysis.
Accomplishments
North Coast Conference on Precision Medicine Travel Award
2018
·
Case Western Reserve University (CWRU)
NIGMS Short Course on Statistical Genetics & Genomics Travel Award
2014
·
NIH/NIGMS
• City Federation of Women's Clubs Endowed Scholarship in Biomedical Sciences
2013
·
University of Texas
Teaching Profile
Courses Taught
2023-2024
PHC6937 Special Topics in Public Health
2023-2024
PHC7979 Advanced Research
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-1597-4719
Areas of Interest
- Bioinformatics
- Cancer epidemiology
- Machine Learning
- Statistical Genetics
Publications
2024
A statistical learning method for simultaneous copy number estimation and subclone clustering with single-cell sequencing data
Genome Research.
34(1):85-93
[DOI] 10.1101/gr.278098.123.
[PMID] 38290978.
2024
OSCAA: A two-dimensional Gaussian mixture model for copy number variation association analysis.
Genetic epidemiology.
[DOI] 10.1002/gepi.22558.
[PMID] 38533840.
2023
A Bayesian framework for pathway-guided identification of cancer subgroups by integrating multiple types of genomic data.
Statistics in medicine.
42(28):5266-5284
[DOI] 10.1002/sim.9911.
[PMID] 37715500.
2023
Data management and techniques for best–worst discrete choice experiments
The Stata Journal: Promoting communications on statistics and Stata.
23(4):1020-1044
[DOI] 10.1177/1536867×231212437.
2022
BISC: accurate inference of transcriptional bursting kinetics from single-cell transcriptomic data.
Briefings in bioinformatics.
23(6)
[DOI] 10.1093/bib/bbac464.
[PMID] 36326081.
2022
BMI-CNV: a Bayesian framework for multiple genotyping platforms detection of copy number variants
Genetics.
222(4)
[DOI] 10.1093/genetics/iyac147.
[PMID] 36171678.
2022
SCANNER: a web platform for annotation, visualization and sharing of single cell RNA-seq data
Database.
2022
[DOI] 10.1093/database/baab086.
[PMID] 35134150.
2022
SCRIP: an accurate simulator for single-cell RNA sequencing data
Bioinformatics.
38(5):1304-1311
[DOI] 10.1093/bioinformatics/btab824.
2021
Integrating genomic correlation structure improves copy number variations detection.
Bioinformatics (Oxford, England).
37(3):312-317
[DOI] 10.1093/bioinformatics/btaa737.
[PMID] 32805016.
2021
Machine learning-based multimodal prediction of language outcomes in chronic aphasia.
Human brain mapping.
42(6):1682-1698
[DOI] 10.1002/hbm.25321.
[PMID] 33377592.
2021
SCISSOR™: a single-cell inferred site-specific omics resource for tumor microenvironment association study
NAR Cancer.
3(3)
[DOI] 10.1093/narcan/zcab037.
[PMID] 34514416.
2021
Shall genomic correlation structure be considered in copy number variants detection?
Briefings in bioinformatics.
22(6)
[DOI] 10.1093/bib/bbab215.
[PMID] 34114005.
2020
A gene expression-based immune signature for lung adenocarcinoma prognosis
Cancer Immunology, Immunotherapy.
69(9):1881-1890
[DOI] 10.1007/s00262-020-02595-8.
[PMID] 32372138.
2020
Joint modeling of eQTLs and parent-of-origin effects using an orthogonal framework with RNA-seq data
Human Genetics.
139(8):1107-1117
[DOI] 10.1007/s00439-020-02162-2.
2020
Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2.
American journal of respiratory and critical care medicine.
201(12):1557-1559
[DOI] 10.1164/rccm.202003-0693LE.
[PMID] 32329629.
2019
An accurate and powerful method for copy number variation detection.
Bioinformatics (Oxford, England).
35(17):2891-2898
[DOI] 10.1093/bioinformatics/bty1041.
[PMID] 30649252.
2019
Brain-Derived Neurotrophic Factor Genotype-Specific Differences in Cortical Activation in Chronic Aphasia.
Journal of speech, language, and hearing research : JSLHR.
62(11):3923-3936
[DOI] 10.1044/2019_JSLHR-L-RSNP-19-0021.
[PMID] 31756156.
Grants
Sep 2024
ACTIVE
The Role of Brain-Bone Marrow-Gut Interaction following Major Trauma
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Oct 2022
– Sep 2023
Assessing Safety and Mobility Benefits of Autonomous Ride Sharing Services Among Veterans in Florida.
Role: Principal Investigator
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Apr 2022
– Aug 2023
COPY NUMBER VARIATION AND LUNG CANCER: DISEASE RISK, PREDICTION AND MECHANISM
Role: Principal Investigator
Funding: NATL INST OF HLTH NHGRI
Jan 2022
ACTIVE
The evolution of copy number variations in the AT-rich Plasmodium genome
Role: Principal Investigator
Funding: UNIV OF VIRGINIA
via NATL INST OF HLTH NIAID
Education
Postdoctoral Associate
2015
·
Yale University
PhD in Biomathematics and Biostatistics
2013
·
UT MD Anderson Cancer Center
Contact Details
Phones:
- Business:
- (352) 294-5917
Emails:
- Business:
- feifeixiao@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 117450
2004 MOWRY RD
GAINESVILLE FL 32611 - Business Street:
-
Room 5227
2004 Mowry Rd
Gainesville FL 32608