Tongjun Gu,
AST SCTST
About Tongjun Gu
Dr. Gu is an Associate Scientist in UF Interdisciplinary Center for Biotechnology Research and a courtesy faculty in UF Department of Biostatistics. She is a member of Division of Quantitative Sciences, UF Health Cancer Center, and a member of UF Center for Genetic Epidemiology and Bioinformatics. Dr. Gu obtained her B.S. on Biomedicine Engineering from Huazhong University of Science and Technology and Ph.D. on Bioinformatics from Institute of Biophysics Chinese Academy of Sciences in China. Then she came to US and did her Postdoc training in The Jackson Laboratory. Before she joined UF, she worked in University of Chicago as a Research Professional.
Additional Positions:
Courtesy Associate Scientist
2022 – Current
·
UF Department of Biostatistics
Accomplishments
Revierwers' Choice Abstracts
2017
·
American Society of Human Genetics
Postdoc fellowship
2012-2014
·
The Jackson Lab
Travel fellowship
2012
·
The 22nd CDB Meeting, RIKEN CDB, Japan
Research Profile
Dr. Gu’s search focuses on developing and applying Artificial Intelligence algorithms and statistical models, particularly deep learning and machine learning, for understanding the complex biological systems and human diseases. She has intensive training and experiences on genetics, genomics, epigenetics, genome wide association studies, cancer biology, RNA sciences and alzheimer’s disease. She is particularly interested in integrating multi-omics data into one model to study their interactions and identify the key elements and the interactions caused the disease to assist the early diagnosis and personalized treatment.
Open Researcher and Contributor ID (ORCID)
0000-0002-8379-0962
Publications
2024
Distinctive genes and signaling pathways associated with type 2 diabetes-related periodontitis: Preliminary study.
PloS one.
19(1)
[DOI] 10.1371/journal.pone.0296925.
[PMID] 38241313.
2024
Identification of tumor rejection antigens and the immunologic landscape of medulloblastoma.
Genome medicine.
16(1)
[DOI] 10.1186/s13073-024-01363-y.
[PMID] 39160595.
2023
Investigating miR-9 as a mediator in laryngeal cancer health disparities.
Frontiers in oncology.
13
[DOI] 10.3389/fonc.2023.1096882.
[PMID] 37081981.
2022
Development of Human Adrenocortical Adenoma (HAA1) Cell Line from Zona Reticularis
International Journal of Molecular Sciences.
24(1)
[DOI] 10.3390/ijms24010584.
[PMID] 36614027.
2022
Fine‐mapping and replication of EWAS loci harboring putative epigenetic alterations associated with AD neuropathology in a large collection of human brain tissue samples
Alzheimer's & Dementia.
19(4):1216-1226
[DOI] 10.1002/alz.12761.
[PMID] 35959851.
2022
Transcriptional profiling of two muscadine grape cultivars “Carlos” and “Noble” to reveal new genes, gene regulatory networks, and pathways that involved in grape berry ripening
Frontiers in Plant Science.
13
[DOI] 10.3389/fpls.2022.949383.
[PMID] 36061784.
2021
Biological features between miRNAs and their targets are unveiled from deep learning models.
Scientific reports.
11(1)
[DOI] 10.1038/s41598-021-03215-w.
[PMID] 34893648.
2021
Genomic and Targeted Approaches Unveil the Cell Membrane as a Major Target of the Antifungal Cytotoxin Amantelide A.
Chembiochem : a European journal of chemical biology.
22(10):1790-1799
[DOI] 10.1002/cbic.202000685.
[PMID] 33527693.
2021
miTAR: a hybrid deep learning-based approach for predicting miRNA targets
BMC Bioinformatics.
22(1)
[DOI] 10.1186/s12859-021-04026-6.
[PMID] 33639834.
2021
Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a
PLOS Genetics.
17(12)
[DOI] 10.1371/journal.pgen.1009934.
[PMID] 34914716.
2021
Transfer of oral bacteria to the fetus during late gestation.
Scientific reports.
11(1)
[DOI] 10.1038/s41598-020-80653-y.
[PMID] 33436911.
2020
Systematic identification of A-to-I editing associated regulators from multiple human cancers.
Computers in biology and medicine.
119
[DOI] 10.1016/j.compbiomed.2020.103690.
[PMID] 32339124.
2019
Author Correction: Integrating multi-platform genomic datasets for kidney renal clear cell carcinoma subtyping using stacked denoising autoencoders.
Scientific reports.
9(1)
[DOI] 10.1038/s41598-019-55817-0.
[PMID] 31852923.
2019
Clinical Relevance of Noncoding Adenosine-to-Inosine RNA Editing in Multiple Human Cancers.
JCO clinical cancer informatics.
3:1-8
[DOI] 10.1200/CCI.18.00151.
[PMID] 31162949.
2019
Integrating multi-platform genomic datasets for kidney renal clear cell carcinoma subtyping using stacked denoising autoencoders.
Scientific reports.
9(1)
[DOI] 10.1038/s41598-019-53048-x.
[PMID] 31723226.
2019
Sex-specific airway hyperreactivity and sex-specific transcriptome remodeling in neonatal piglets challenged with intra-airway acid.
American journal of physiology. Lung cellular and molecular physiology.
316(1):L131-L143
[DOI] 10.1152/ajplung.00417.2018.
[PMID] 30407862.
2018
Dicer cleaves 5′-extended microRNA precursors originating from RNA polymerase II transcription start sites
Nucleic Acids Research.
46(11):5737-5752
[DOI] 10.1093/nar/gky306.
[PMID] 29746670.
2017
GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR.
PloS one.
12(7)
[DOI] 10.1371/journal.pone.0180817.
[PMID] 28686716.
2017
Modification of the Streptococcus mutans transcriptome by LrgAB and environmental stressors.
Microbial genomics.
3(2)
[DOI] 10.1099/mgen.0.000104.
[PMID] 28348880.
2017
Remodeling of the Streptococcus mutans proteome in response to LrgAB and external stresses.
Scientific reports.
7(1)
[DOI] 10.1038/s41598-017-14324-w.
[PMID] 29070798.
2016
Abstract 4272: Organoids and patient-derived tumor xenograft of pancreatic adenocarcinoma share morphological and genetic features with the primary tumor
Cancer Research.
76(14_Supplement):4272-4272
[DOI] 10.1158/1538-7445.am2016-4272.
2016
Genetic Architectures of Quantitative Variation in RNA Editing Pathways.
Genetics.
202(2):787-98
[DOI] 10.1534/genetics.115.179481.
[PMID] 26614740.
2014
Role of microRNAs in renal ischemia-reperfusion injury: an update
Academic Journal of Second Military Medical University.
33(12):1365-1370
[DOI] 10.3724/sp.j.1008.2013.01365.
2012
Canonical A-to-I and C-to-U RNA editing is enriched at 3’UTRs and microRNA target sites in multiple mouse tissues.
PloS one.
7(3)
[DOI] 10.1371/journal.pone.0033720.
[PMID] 22448268.
2012
Deregulated sex chromosome gene expression with male germ cell-specific loss of Dicer1.
PloS one.
7(10)
[DOI] 10.1371/journal.pone.0046359.
[PMID] 23056286.
2012
Pla2g12b and Hpn Are Genes Identified by Mouse ENU Mutagenesis That Affect HDL Cholesterol
PLoS ONE.
7(8)
[DOI] 10.1371/journal.pone.0043139.
[PMID] 22912808.
2009
Alu-directed transcriptional regulation of some novel miRNAs.
BMC genomics.
10
[DOI] 10.1186/1471-2164-10-563.
[PMID] 19943974.
2007
Common Substructure Extraction of Proteins by Geometric Invariants
2007 10th IEEE International Conference on Computer-Aided Design and Computer Graphics.
[DOI] 10.1109/cadcg.2007.4407861.
2007
Protein Structure Superposition by Curve Moment Invariants and Iterative Closest Point
2007 1st International Conference on Bioinformatics and Biomedical Engineering.
[DOI] 10.1109/icbbe.2007.10.
Shape Representation and Invariant Description of Protein Tertiary Structure in Applications to Shape Retrieval and Classification
Advances in Geometric Modeling and Processing.
556-562
[DOI] 10.1007/978-3-540-79246-8_47.
Contact Details
Phones:
- Business:
- (414) 937-3884
Emails:
- Business:
- tgu@ufl.edu
Addresses:
- Business Mailing:
-
PO BOX 103622
GAINESVILLE FL 326110001 - Business Street:
-
ICBR
2033 MOWRY RD
CANCER & GENETICS RESEARCH COMPLEX (CGRC)
GAINESVILLE FL 326103010