Gut Microbiome, Aging and Cardiometabolic Diseases in American Indians

This project was funded by NIA (R01AG068865, 9/10/2020-8/30/2025, PI: Jinying Zhao). The goal of this project is to identify key gut microbiome features associated with cardiometabolic traits in American Indians in the Strong Heart Study (SHS). We will collect fecal samples from 1500 participants scheduled to visit SHS Phase VII, conduct deep metagenomic sequencing and identify gut microbiome features associated with biological aging and age-related cardiometabolic diseases in this high-risk minority population.